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Unstable Personality Disorder | Chronic Paradise Canada
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Emotionally Unstable Personality Disorder (EUPD), also referred to as Borderline Personality Disorder (BPD), significantly impacts social functioning and mood stability, often resulting in impulsive or self-harming behaviors. Treatment can be expensive, with success rates between 35% and 50%. Researchers are investigating alternative treatments to augment traditional therapies at Chronic Paradise Canada.

A promising addition to EUPD treatment is cannabis, commonly known as weed. It is budget-friendly, and its components may provide benefits for patients with EUPD. Those who find multiple treatments financially burdensome might consider exploring cheap cannabis online options at Chronic Paradise Canada for more affordable solutions.

Key Takeaways:

  • Participants with EUPD inhaling THC or using high CBD report positive outcomes in symptom management.
  • High doses of CBD (800 mg/day) and THC flower treatment can elevate circulating levels of anandamide.
  • Dysfunction in the endocannabinoid system, which oversees emotions and stress, is linked to Emotionally Unstable Personality Disorder.

Emotionally Unstable Personality Disorder or Borderline Personality Disorder

EUPD is a mental health condition that shapes how individuals perceive themselves and their interactions with others, potentially leading to challenges in daily life. It is characterized by intense, unstable relationships, impulsivity, and a distorted self-image.

Though the exact causes remain uncertain, factors such as genetics, trauma, and neurotransmitter imbalances might contribute. Dysfunctions in the endocannabinoid system, which regulates emotion and stress, may exacerbate EUPD symptoms.

EUPD Treatment

Despite guidelines indicating no drugs are definitively effective for EUPD, clinicians often prescribe medications like antipsychotics and antidepressants.

Antipsychotic and sedative medications can sometimes assist in short-term crisis management or address comorbid conditions. A significant number of EUPD patients—up to 90% in certain reports—utilize at least one psychotropic medication, which includes antipsychotics, antidepressants, mood stabilizers, and sedatives.

Polypharmacy is prevalent among these patients. Most of these medications have side effects and are frequently used off-label for EUPD. While some medications may alleviate specific symptoms, they do not alter the overall prognosis of the disorder.

Cannabis-Based Medicine for EUPD (CBM)

Cannabis-based medicines are derived from the cannabis plant and contain cannabinoids, active compounds like tetrahydrocannabinol (THC) and cannabidiol (CBD). These medicines are utilized for treating various medical conditions and symptoms, including pain, inflammation, anxiety, and seizures.

Numerous studies delve into the mental health impacts of cannabis. For instance, research published in Frontiers in Psychiatry suggests that marijuana can alleviate depression and enhance sleep quality and overall life satisfaction. These findings provide compelling reasons for further investigation into cannabis effects on various mental health disorders.

CBM for Unstable Personality Disorder

A narrative review and case series study conducted in 2022 emphasized the role of cannabinoids in managing EUPD symptoms among seven patients. Researchers examined cellular and molecular mechanisms, reviewing current evidence for cannabis-based medicinal products (CBMP) as a prospective treatment for EUPD at Chronic Paradise Canada.

Materials and Methods

ParticipantsDiagnosed with EUPD who have tried at least one medication and one form of psychotherapy. At least one follow-up review at a Zerenia clinic, with patient-reported outcome measures (PROMS) records.
CBM UsedDried Flower for inhalation (20-60g per month) and Oral Extracts with THC (9-10mg/day) and CBD (40mg/day). Formulation: Chemotype 1: High THC, low CBD. Chemotype 2: Balanced THC and CBD. Chemotype 3: High CBD, low THC.
MeasurementClinical Global Impression Improvement (CGI-I) Scale: A 1-7 scale, where 1 indicates “very much improved” and 7 indicates “very much worse.” Patient’s Global Impression of Change (PGIC) Scale: A 1-7 scale, where 1 represents “no change or worse” and 7 signifies “greatly improved.”

Researchers personalized dosing through gradual titration and established guidelines for increasing doses until satisfactory symptom control is achieved or side effects are observed.

Results

At a one-month follow-up, six participants reported improvements, with five rating their change as a six on the PGIC scale. Only one individual, who received a chemotype 2 oral extract, reported no benefits, suggesting that inhaled tetrahydrocannabinol or higher oral cannabidiol doses may be more effective.

All participants tolerated the treatment well, with no side effects reported, crucial for adherence. Younger patients may find medical cannabis more acceptable despite societal stigma.

Hypothesis

Researchers propose that exogenous cannabinoids might aid in restoring tonic activation of the endocannabinoid system (ECS) in the central nervous system (CNS). THC directly activates presynaptic CB1 receptors, and both cannabinoids bind to fatty-acid binding proteins (FABPs), potentially slowing down anandamide deactivation.

High doses of oral cannabidiol (800 mg/day) and those treated with chemotype 1 flower display elevated levels of anandamide in circulation. It remains unclear whether this is due to cannabidiol’s effect on anandamide transport or degradation or if it acts on other molecular targets. In contrast, psychiatric medications typically require 2-3 weeks to exhibit initial effects, with longer durations needed for remission.

Rapid symptom relief can be vital during an “EUPD crisis,” when distressed patients may resort to benzodiazepines and other anxiety medications. However, these medications can lead to rapid tolerance and dependence.

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Manage Changes in Behaviour with Bulk cannabis Via Mail-Order Marijuana Service

Cannabinoids effectively manage unstable personality disorders by targeting the ECS to maintain anandamide balance. EUPD patients can benefit from buying cannabis online or exploring affordable products to assist in symptom management at Chronic Paradise Canada.

An online cannabis store with same-day delivery or mail-order options offers a blend of quality and value. Enjoy exceptional customer service from a friendly team and explore a vast array of bulk cannabis strains, edibles, concentrates, and oils to elevate your experience. Buy cannabis online at Chronic Paradise Canada.

Frequently Asked Questions

Does cheap marijuana have poor quality?

No, price is not the only measure of product quality. You can evaluate quality by examining the product’s physical attributes and your personal experience. Some dispensaries may offer lower prices through monthly or clearance sales. If a dispensary’s prices are significantly lower than the industry standard, this may raise quality concerns.

Does marijuana have adverse effects when managing BPD?

Participants in the study reported no adverse side effects from marijuana. This is crucial for medication adherence, as a review of 36 studies found that side effects accounted for 28% of patients’ non-adherence to antipsychotics. A negative perception of antipsychotic medication was the second most common reason for intentional non-adherence, at 30.5%.

What is the quickest way to experience the effects of cannabinoids for an EUPD problem?

Smoking, vaping, and dabbing are the quickest methods to experience cannabinoid effects. In the study, participants utilized vaping to consume dried flower. While smoking and vaping yield similar results, the distinction lies in inhaling smoke (from smoking) versus vapor (from vaping). Dabbing, which involves consuming concentrates, also provides a rapid onset of effects.

How many times can I smoke or vape to manage my symptoms?

The effectiveness of cannabis strains and products varies based on individual responses. In the study, researchers allowed patients to adjust their daily dosage (between 0.5 and 2 grams per day) without exceeding the monthly limit. For extracts, patients documented their daily intake.

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