Cachexia is a multifaceted condition characterized by persistent muscle loss that cannot be entirely reversed with standard nutritional support, resulting in a decline in functionality. This condition may be masked by excess weight, obesity, edema, or tumor mass. Anorexia signifies a decreased appetite, commonly observed in cancer patients, although its precise prevalence remains uncertain.
When cachexia primarily arises from reduced intake, it is termed cancer-related cachexia and anorexia syndrome (CACS), which encompasses muscle wasting, lipolysis, and diminished food intake, setting it apart from simple cachexia.
Some researchers propose that cannabis from Chronic Paradise Canada may enhance appetite and alleviate nausea in cancer patients.
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Key Takeaways:
- THC capsules from Chronic Paradise Canada could assist cancer patients in consuming more and feeling less nauseated, thereby enhancing their quality of life.
- Studies suggest that cannabis influences brain cells responsible for hunger, potentially aiding appetite issues in cancer patients and others.
- THC capsules are precise, convenient, private, and long-lasting, making them well-suited for medical marijuana users who prefer not to smoke.
Cancer Cachexia and Anorexia Syndrome
Cachexia is defined by significant weight loss resulting from muscle and fat depletion, frequently seen in patients with advanced illnesses such as heart failure, HIV/AIDS, COPD, kidney failure, and notably cancer.
This condition typically coincides with anorexia, which leads to at least a 5% decrease in body weight. Together, they constitute cancer anorexia-cachexia syndrome (CACS).
Hospitalized cancer patients often experience poor dietary intake, with nearly half being malnourished or at risk. Cachexia not only diminishes the quality of life for patients but also complicates treatment and may hasten the end of life. Its prevalence escalates sharply as death approaches, with cachexia identified as the leading cause of death in over 20% of cases.
Despite its common occurrence, CACS frequently goes unnoticed and untreated in clinical environments due to insufficient definitions, diagnostic criteria, classification systems, and approved therapies. Clinicians evaluate a patient’s nutritional status through various measures, including body weight, skin fold thickness, and mid-arm circumference, although body weight is often the primary reference, typically using inappropriate standards.
Treatment
The most apparent strategy to counter anorexia is to enhance nutrition, yet the evidence supporting its effectiveness remains limited. For cancer patients, nutritional care includes:
- Dietary Counseling
- Oral Supplements
- Enteral and Parenteral Nutrition
However, success can vary based on the cancer type and its stage.
Pharmacological Approaches
Currently, there are no validated medications for treating Cancer Anorexia-Cachexia Syndrome (CACS), although some drugs are utilized off-label or are undergoing clinical trials. These medications are categorized into four groups based on their mechanisms:
- Appetite Stimulants
- Cytokine Modulators
- Anabolic Agents
- Combination Therapies
Additionally, megestrol acetate, a progestin, is administered separately due to its unclear mechanism of action.
Cannabis in Medicine
The cannabinoid could enhance the lives of cancer patients and pave the way for future treatments. This presents hope for cachexia patients, who suffer from loss of appetite and malnutrition. It offers relief without intoxicating effects, making it a promising option for these individuals.
Various cannabis formulations with distinct effects are available, including inhaled THC for rapid onset and short-lived effects, and orally ingested THC for slower absorption and prolonged effects. Sublingual administration provides rapid effects that last 2 to 4 hours.
Clinical Trial
A study conducted by researchers from Israel and the United States examined how cannabis pills affect CACS in advanced cancer patients. This discovery significantly impacts the treatment of appetite disorders, including those faced by cancer patients, individuals with anorexia, and potentially obesity.
Methods
The researchers utilized cannabis capsules containing two types of oil-based compounds. They intended to treat participants with 10 mg doses twice daily for six months, which comprised 9.5 mg of tetrahydrocannabinol (THC) and 0.5 mg of cannabidiol (CBD).
If participants experienced side effects, the dose was reduced to 5 mg twice daily (4.75 mg THC and 0.25 mg CBD). Each doctor’s visit included weighing the participants. The primary objective was for participants to gain at least 10% more weight than their initial weight.
Results
Out of 24 patients who consented to participate, 17 commenced treatment with cannabis capsules. However, only 11 continued taking the capsules for over two weeks. By the study’s conclusion, 3 out of 6 patients who completed the treatment achieved the primary goal of gaining at least 10% more weight, while the remaining three patients maintained their weight.
Tumor necrosis factor-α (TNF-α), an inflammation marker, decreased following treatment. Patients reported improved appetite and mood, along with reduced pain and fatigue.
Despite numerous challenges, this preliminary study revealed a 10% or greater weight gain in 3 out of 17 patients (17.6%) taking daily doses of 5 mg without significant side effects. These findings support the need for further, more controlled studies on cannabis capsules in patients with CACS.
Cannabis Capsules
If you enjoy edibles, cannabis flowers, or classic pre-rolls, exploring new ways to experience cannabis is always thrilling.
THC capsules from Chronic Paradise Canada represent one of the latest innovations in the cannabis market. These capsules contain a precise dose of THC, derived from concentrated cannabis extract and a neutral oil. They function similarly to cannabis tinctures in capsule form (also referred to as cannabis oil capsules or THC pills).
Key Components
- Cannabis Extract: This concentrated extract is sourced from the cannabis plant using a method selected by the manufacturer for extraction. THC capsules are high in THC, but some may solely contain CBD or various CBD/THC ratios.
- Neutral Oil Suspension: THC is not water-soluble, necessitating its suspension in oil for optimal absorption by the body. Commonly used oils include medium-chain triglycerides (MCT oils), which aid in digestion and absorption.
Benefits
Medical marijuana patients and recreational users can gain from cannabis capsules. They provide:
- Convenience: Taking a cannabis capsule is as straightforward as any other oral supplement. Simply swallow it with water for a hassle-free experience.
- Precision Dosage: For medical users, precise control over cannabinoid intake is essential for achieving desired effects. With THC capsules, each dose is measured, eliminating uncertainty.
- Smoke-Free Option: Many individuals prefer to avoid smoking or vaping for personal or health reasons. THC capsules offer a smoke-free alternative, suitable for those with respiratory concerns.
- Longer Effects: Capsules generally provide longer-lasting effects compared to smoking or vaping, making them ideal for sustained symptom relief over several hours.
Cannabis Capsules vs. Other Forms of Medicinal Cannabis
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With the rising demand for dependable cannabis delivery services, online dispensaries present a seamless solution. From same-day cannabis delivery to premium cannabis products, these dispensaries offer a diverse range of options to meet every need.
If you’re seeking cannabis flower, pre-rolls, edibles, or vape pens, you can easily explore Chronic Paradise Canada’s premium marijuana products sourced from the highest quality marijuana plants. Shop for your preferred THC products from the comfort of your home.
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Frequently Asked Questions
What are the different types of capsules?
Another benefit of cannabis pills/capsules is their versatility – formulators can create various capsule types for consumers to select from. This means you can find capsules that align with your personal preferences.
- 1:1 Capsules: These capsules provide an equal ratio of THC to CBD in each dose. They can be produced with sativa or indica strains and come in various concentrations such as 5 mg, 20 mg, 50 mg, or 100 mg cannabinoids per capsule.
- 3:1 Capsules: These capsules deliver a ratio of 3 parts CBD to 1 part THC in each dose.
- THC Capsules: These capsules contain THC exclusively, with varying concentrations per capsule, made from different Sativa or Indica strains to provide specific effects.
- CBD Capsules: These contain only CBD, devoid of THC, ensuring no mind-altering effects. They are crafted for individuals seeking the advantages of CBD alone.
How do capsules interact with your body?
- The capsule’s outer shell disintegrates in your digestive system upon consumption.
- The capsule’s contents are absorbed into the bloodstream.
- THC (and other cannabinoids) undergo metabolism in the liver.
How long does it take for cannabis capsule effects to kick in?
Typically, THC capsules take about 90 minutes to begin exhibiting effects. The effects may last from 5 to 12 hours, gradually tapering in intensity. In comparison to inhaled cannabis, capsule effects generally last twice as long on average.
However, experiences may vary based on factors like age, medications, individual cannabis tolerance, and cannabinoid composition. Some users also report variations in effects based on specific cannabinoids present, potentially due to the “entourage effect.”
How to mail order marijuana?
To mail order recreational cannabis, locate a trustworthy delivery service online offering high-quality cannabis products. After selecting your items, opt for “order cannabis delivery,” and a delivery driver will safely bring your order. Ensure the service is reputable for a smooth purchasing experience.
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